PLGA Cy3 Capped, MW 10K is a high-molecular-weight fluorescent biodegradable PLGA copolymer with terminal Cy3 fluorophore labeling. Available in 50:50, 65:35, 75:25, 85:15 and custom lactide-glycolide ratios, it is optimized for long-term stable fluorescence tracking, prolonged nanoparticle imaging, and long-cycle in vitro and in vivo biodegradable carrier tracing research.
Key Features and Benefits
Cy3 Fluorescent Capped: Terminal Cy3 fluorescent labeling delivers stable red-orange fluorescence, enabling direct, real-time optical tracking and qualitative/quantitative detection without additional staining. Uniform end-capping ensures durable fluorescent signal retention during long-term degradation.
Lactide Ratio Available: Supports standard 50:50, 65:35, 75:25, 85:15 and custom ratios to flexibly adjust polymer hydrophilicity, degradation rate and formulation performance for diverse long-cycle experimental and formulation needs.
MW 10K: High molecular weight features dense polymer chain entanglement and excellent structural rigidity, providing superior particle stability compared to low and medium MW PLGA. It delivers prolonged and uniform degradation behavior, perfectly suited for long-term sustained-release fluorescent particle fabrication.
Biocompatible & Biodegradable: Possesses excellent biosafety and undergoes complete hydrolytic degradation into non-toxic lactic acid and glycolic acid, ideal for long-term biological imaging and extended in vivo biomedical tracking applications.
Fluorescence Stable & Reliable: Precise terminal fluorophore modification avoids fluorescence shedding and quenching, maintaining stable and consistent signal intensity throughout long-term particle circulation and polymer degradation processes.
Applications
Long-Term Fluorescence Particle Tracing: Applied for prolonged real-time tracking and tissue distribution analysis of PLGA nanoparticles and microspheres in biological systems.
Prolonged Drug Delivery Imaging: Enables visual monitoring of long-cycle drug carrier release, in vivo accumulation, metabolism and retention behavior for sustained release formulation research.
Biomedical Fluorescent Labeling: Acts as a stable self-fluorescent polymer matrix for long-term biodegradable material imaging and biological distribution evaluation.
Long-Cycle Formulation & Stability Research: Supports intuitive assessment of long-term polymer degradation, particle structural stability and sustained delivery efficiency of advanced drug carrier systems.
Storage and Handling
Storage: Store at –20 °C in a sealed, dry, light-proof and moisture-proof container.
Handling: Avoid strong light exposure, repeated freeze-thaw cycles and high temperature to prevent fluorescence quenching and polymer hydrolysis, ensuring long-term sample stability.
PLGA Cy3 Capped, MW 10K integrates high-molecular-weight long-cycle degradation performance, tunable PLGA ratio and ultra-stable Cy3 fluorescence, specially designed for long-term visual tracking, prolonged sustained fluorescent imaging and advanced biodegradable carrier research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.