PLGA Cy3 Capped, MW 5K is a medium-molecular-weight fluorescent biodegradable PLGA copolymer with terminal Cy3 fluorophore labeling. Available in 50:50, 65:35, 75:25, 85:15 and custom lactide-glycolide ratios, it is optimized for steady fluorescence tracking, sustained nanoparticle imaging, and in vitro and in vivo biodegradable carrier tracing research.
Key Features and Benefits
Cy3 Fluorescent Capped: Terminal Cy3 fluorescent labeling delivers stable red-orange fluorescence, enabling direct, real-time optical tracking and qualitative/quantitative detection without additional staining.
Lactide Ratio Available: Supports standard 50:50, 65:35, 75:25, 85:15 and custom ratios to flexibly adjust polymer hydrophilicity, degradation rate and formulation performance for diverse experimental needs.
MW 5K: Medium molecular weight balances excellent organic solubility and moderate, steady degradation rate, providing better particle structural stability than low-MW PLGA, ideal for sustained-release fluorescent nanoparticle and microsphere fabrication.
Biocompatible & Biodegradable: Features good biosafety and complete hydrolytic degradation into lactic acid and glycolic acid, suitable for biological imaging and medium-term biomedical tracking applications.
Fluorescence Stable & Reliable: Uniform end-group labeling ensures consistent fluorescence intensity, effectively avoiding fluorophore shedding and signal attenuation during particle formulation and degradation.
Applications
Fluorescence Particle Tracing: Used for real-time tracking and distribution observation of PLGA nanoparticles and microspheres in biological systems.
Sustained Drug Delivery Imaging: Enables visual monitoring of medium-term drug carrier release, accumulation and metabolic behavior in vitro and in vivo.
Biomedical Fluorescent Labeling: Serves as a self-fluorescent polymer matrix for biodegradable material imaging and biological distribution research.
Formulation & Mechanism Research: Facilitates intuitive evaluation of polymer degradation, particle stability and sustained carrier delivery efficiency.
Storage and Handling
Storage: Store at –20 °C in a sealed, dry, light-proof and moisture-proof container.
Handling: Avoid strong light exposure, repeated freeze-thaw cycles and high temperature to prevent fluorescence quenching and polymer hydrolysis.
PLGA Cy3 Capped, MW 5K integrates medium-molecular-weight steady degradation performance, tunable PLGA ratio and stable Cy3 fluorescence, specially designed for medium-term visual tracking, sustained fluorescent imaging and biodegradable carrier research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.