PLGA Biotin Capped, MW 2K is a low-molecular-weight biodegradable copolymer with terminal biotin functionalization with optional multiple lactide-glycolide ratios including 50:50, 75:25, 85:15 and custom ratio service, supporting targeted drug delivery, biotin-avidin conjugation, particle fabrication, and advanced biomaterial research.
Key Features and Benefits
Biotin Capped: Provides terminal biotin functionality for high-affinity avidin/streptavidin binding and specific biomolecular conjugation.
Lactide Ratio Available: Provides optional PLGA ratios of 50:50, 75:25, 85:15, and customizable tailored ratios to meet different degradation rate and formulation requirements for stable polymeric formulations.
MW 2K: Low molecular weight supports convenient solution processing, good solubility in organic solvents, and relatively rapid and controllable polymer degradation.
Biocompatible & Biodegradable: Degrades naturally into non-toxic lactic acid and glycolic acid under physiological conditions with excellent biosafety.
Highly Versatile Functional Polymer: Enables specific biological targeting and surface modification for nanoparticles, microspheres, biodegradable coatings, and functional polymer matrices.
Applications
Targeted Drug Delivery: Supports construction of active-targeted biodegradable delivery systems and precise controlled-release formulations.
Biotin-Avidin Bioconjugation: Utilizes high-specificity biotin-streptavidin interaction for coupling with avidin/straptavidin-labeled proteins, antibodies, and probes.
Functional Polymer Modification: Serves as a biotin-functionalized PLGA building block for further biological derivatization and material functionalization.
Polymeric Particle Fabrication: Enables facile preparation and specific surface functionalization of PLGA nanoparticles and microspheres for biomedical use.
Biomedical Biomaterials: Suitable for developing targeted biodegradable scaffolds, surface-modified coatings, and diagnostic & therapeutic biomaterials.
Storage and Handling
Storage: Store at –20 °C in a sealed, dry, moisture-proof container under inert atmosphere if possible.
Handling: Protect from moisture, repeated freeze-thaw cycles, and excessive heat to prevent premature hydrolysis and maintain biotin activity and polymer integrity.
PLGA Biotin Capped, MW 2K combines low molecular weight, tunable biodegradability, and specific terminal biotin functionality specifically for targeted drug delivery, high-affinity bioconjugation, and functional biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.