PLGA Ester Capped (85:15), MW 150K is a high-molecular-weight biodegradable copolymer with an 85:15 lactide:glycolide ratio and ester end groups. Its lactide-rich composition specifically supports sustained drug delivery, controlled degradation, and durable biomaterial systems.
Key Features and Benefits
- Ester Capped: Provides ester end groups that reduce terminal carboxyl functionality.
- 85:15 PLGA Ratio: High lactide content supports slower water uptake and extended degradation compared with glycolide-rich PLGA compositions.
- MW 150K: Provides high molecular weight for durable polymer matrices and prolonged-release formulations.
- Biodegradable: PLGA hydrolyzes into lactic acid and glycolic acid under physiological conditions.
- Versatile Polymer: Supports particles, films, implants, scaffolds, and other biodegradable delivery systems.
Applications
- Sustained Drug Delivery: Extends drug release through biodegradable polymer matrices.
- Long-Acting Formulations: Supports development of implants, depots, and other prolonged-release systems.
- Microparticles: Forms biodegradable microspheres and related drug-loaded particles.
- Biomaterials: Supports scaffolds, films, coatings, and durable biodegradable matrices.
- Formulation Research: Enables studies of polymer degradation, drug release, and lactide-rich PLGA performance.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to limit premature hydrolysis and polymer degradation.
PLGA Ester Capped (85:15), MW 150K combines high molecular weight, ester end groups, and a lactide-rich composition to specifically support sustained drug delivery, long-acting formulations, durable polymer matrices, and advanced biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.