PLGA Ester Capped (85:15), MW 10K is a biodegradable copolymer with an 85:15 lactide:glycolide ratio, ester end groups, and an approximate molecular weight of 10 kDa. Its lactide-rich composition specifically supports controlled drug delivery, particle formulation, and biomaterial development.
Key Features and Benefits
- Ester Capped: Provides ester end groups that reduce terminal carboxyl functionality.
- 85:15 PLGA Ratio: High lactide content supports slower water uptake and extended degradation compared with glycolide-rich PLGA compositions.
- MW 10K: Offers low molecular weight for efficient processing and flexible formulation development.
- Biodegradable: PLGA hydrolyzes into lactic acid and glycolic acid under physiological conditions.
- Versatile Polymer: Supports particles, films, matrices, coatings, and other biodegradable delivery systems.
Applications
- Drug Delivery: Controls drug release through biodegradable polymer matrices.
- Controlled-Release Formulations: Supports development of biodegradable delivery systems with tunable release profiles.
- Microparticles: Forms biodegradable microspheres and related drug-loaded particles.
- Nanoparticles: Supports preparation of biodegradable polymeric nanoparticles and drug carriers.
- Biomaterials: Enables development of films, coatings, matrices, and other biodegradable materials.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to limit premature hydrolysis and polymer degradation.
PLGA Ester Capped (85:15), MW 10K combines ester end groups, a lactide-rich composition, and low molecular weight to specifically support controlled drug delivery, particle formulation, polymer matrices, and advanced biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.