PLGA Acid Capped (PLGA-COOH, 85:15), MW 10K is a medium molecular weight, carboxyl-terminated poly(D,L-lactide-co-glycolide) random copolymer with a fixed lactide-glycolide molar ratio of 85:15. This functionalized biodegradable polymer features highly active terminal carboxylic acid groups, enabling stable EDC/NHS crosslinking and efficient bioconjugation with various amine-containing biomolecules, including functional peptides, bioactive proteins, and targeted modification ligands. It features intact and stable molecular chain structures with steady hydrolytic degradation properties, achieving consistent and long-lasting sustained drug release effects for biomedical formulations. With excellent inherent biocompatibility and biological safety, the polymer fully degrades into non-toxic lactic acid and glycolic acid within biological systems. Supplied as uniform white amorphous powder, it features excellent solubility in common organic solvents such as DCM, chloroform, THF and acetone. Strict sealed storage at -20°C in dry and dark conditions is essential to preserve molecular chain integrity and stable product performance.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.