Semax
Semax CAS:80714-61-0 is a synthetic neuropeptide with neuroprotective, nootropic, and cognitive-enhancing properties, structurally derived from adrenocorticotropic hormone (ACTH 4–10) but without hormonal side effects. It is widely studied in preclinical and limited clinical research for its ability to support brain function, reduce oxidative stress, and enhance nervous system recovery.
Description
Semax is a synthetic peptide fragment that acts on the central nervous system by regulating the expression of neurotrophic factors, enhancing dopamine and serotonin metabolism, and reducing oxidative damage in brain tissue. It supports neuronal survival, improves cerebral blood flow, and helps maintain cognitive function under stress, fatigue, or hypoxic conditions. Its stable structure allows for good bioavailability and penetration across the blood-brain barrier in research models.
Key Features
- Strong neuroprotective effect, protecting neurons from hypoxia, ischemia, and oxidative damage.
- Enhances cognitive functions including memory, attention, concentration, and learning ability.
- Supports mood balance and helps reduce mental fatigue and stress-related discomfort.
- Promotes the synthesis of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF).
- Improves cerebral microcirculation and oxygen utilization in brain tissue.
- Stable peptide structure with favorable safety profile in research settings.
Preclinical & Clinical Research Applications
- Cognitive enhancement and research on memory and learning disorders.
- Neuroprotection in models of cerebral ischemia, stroke, and traumatic brain injury.
- Support for recovery from nervous system damage and degenerative conditions.
- Reduction of mental fatigue, stress, and asthenia in research and limited clinical use.
- Studies on attention deficit, focus disorders, and cognitive performance optimization.
- Support for neurological rehabilitation and functional recovery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.





