Annexin V (or Annexin A5), His Tag is a recombinant protein with a polyhistidine (His) tag for easy purification and detection. It specifically binds to phosphatidylserine (PS) on apoptotic cell membranes, making it useful for studying apoptosis, cell signaling, and membrane interactions. The His tag allows for straightforward immobilization, purification, or labeling using nickel-based resins or anti-His antibodies.
Key Features:
- Specific PS Binding: Recognizes PS on apoptotic cells.
- His Tag for Detection: Facilitates purification and labeling.
- Recombinant Purity: High consistency and batch-to-batch reliability.
Annexin V, His Tag Applications:
- Apoptosis Detection: Early apoptosis assays in flow cytometry and microscopy.
- Protein Purification: Use with Ni-NTA or similar affinity resins.
- Membrane Studies: Investigating lipid-protein interactions.
- Drug Screening: Screening compounds that affect apoptosis pathways.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.