DOTAM-mono-acid, CAS Number 913528-04-8, is a versatile chelating agent frequently used in bioconjugation, radiolabeling, and molecular imaging applications.
Overview
- Full Name: 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid monoamide.
- CAS Number: 913528-04-8.
- Chemical Formula: C16H28N4O9.
- Molecular Weight: 420.42 g/mol.
DOTAM-mono-acid Applications
- Bioconjugation: The mono-acid functional group allows for easy attachment to various biomolecules, such as proteins and peptides.
- Radiolabeling: DOTAM acts as a strong chelator, binding metal ions like Gallium-68 (Ga-68) for PET imaging or Lutetium-177 (Lu-177) for targeted therapies.
- Imaging: Commonly used in developing imaging agents for PET, SPECT, and MRI, enhancing diagnostic tools in biomedical research.
Properties
- Mono-Acid Group: Offers a reactive site for bioconjugation, enabling easy attachment to other molecules.
- Chelating Ability: DOTAM forms stable complexes with metal ions, ensuring reliability in radiolabeled compounds.
Handling and Storage
- Storage: Store in a cool, dry place away from light to maintain stability.
- Handling: Use standard protective measures to avoid unwanted reactions during synthesis.
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