DOTAGA-tetra (t-Bu ester), CAS Number 306776-79-4, is a chelating compound commonly used in radiolabeling and molecular imaging applications. H
Key Applications
- Bioconjugation: Provides strong attachment to biomolecules, such as proteins and peptides, for targeted labeling.
- Radiolabeling: DOTA-based chelator that binds metal ions like Gallium-68 (Ga-68) for PET imaging or Lutetium-177 (Lu-177) for cancer therapy.
- Imaging: Commonly used to develop stable imaging agents for PET, SPECT, and MRI, enhancing diagnostic tools in biomedical research.
Properties
- tert-Butyl Ester Protection: Protects carboxyl groups during synthesis, ensuring stability until deprotection for metal chelation.
- Chelating Ability: DOTAGA forms strong and stable complexes with metal ions, ensuring reliable radiolabeling.
Handling and Storage
- Storage: Keep in a cool, dry place, away from light to maintain stability.
- Handling: Use standard protective equipment to avoid unintended reactions during synthesis.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
