Val-Cit-OH

(S)-Valine-(S)-Citrulline Hydroxy Acid (CAS: 159858-33-0) is a valuable compound commonly used in peptide synthesis and drug delivery systems. It features the amino acid sequence of Valine-Citrulline (Val-Cit), making it useful for creating self-cleaving peptide linkers, particularly in prodrug designs. The structure of (S)-Valine-(S)-Citrulline Hydroxy Acid enables controlled release of the active drug when cleaved, which is ideal for targeted therapies.

Key Features:

• Valine-Citrulline (Val-Cit) Sequence: The combination of Valine and Citrulline allows for selective cleavage, improving drug activation and delivery.
• Self-Cleaving Linker: Ideal for prodrug applications, where the compound cleaves under specific conditions to release the active drug.
• High Purity: Provides consistent and reliable results for various applications, ensuring the highest standards of research and production.
• Solubility: Highly soluble in aqueous solutions, providing flexibility for diverse experimental conditions.
• Stable: Offers excellent stability under normal conditions, making it suitable for long-term use in various formulations.

Applications:

• Prodrug Design: Utilized to create prodrugs that release active pharmaceutical agents in a controlled manner.
• Peptide Synthesis: Serves as a building block in the creation of peptide-based therapeutics and linkers.
• Drug Delivery Systems: Plays a key role in drug delivery technologies that require targeted, controlled release mechanisms.
• Cancer Therapy: The compound is particularly important for targeted cancer treatments, where selective drug release improves therapeutic efficacy.
• Bioconjugation: Used to attach therapeutic agents to peptides or antibodies, enabling controlled action in drug discovery.

Conclusion:

(S)-Valine-(S)-Citrulline Hydroxy Acid (CAS: 159858-33-0) is an essential compound for drug delivery, peptide synthesis, and prodrug design. Its self-cleaving properties and high purity make it indispensable for targeted therapies, particularly in cancer treatment and drug discovery. With its solubility and stability, it is an ideal choice for research and clinical applications.