PEG7-Tos
PEG7-Tos is a high-purity PEG reagent featuring a tosyl (p-toluenesulfonyl) leaving group connected by a PEG7 spacer, specifically enabling efficient nucleophilic substitution reactions with enhanced solubility and flexibility.
Key Features and Benefits
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Tosyl Group – Efficient leaving group for substitution reactions with nucleophiles such as amines, thiols, and alkoxides.
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PEG7 Spacer – Improves aqueous solubility, reduces steric hindrance, and increases linker flexibility.
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High Purity – Suitable for reliable conjugation, functionalization, and derivatization.
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Versatility – Compatible with a wide range of bioconjugation and surface modification workflows.
Applications
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Functionalization of biomolecules with nucleophilic groups
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Surface modification for material science and nanotechnology
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Preparation of PEGylated derivatives and linkers
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Intermediate for drug delivery systems and diagnostics
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents (e.g., DMF, DMSO). Avoid repeated freeze–thaw cycles.
PEG7-Tos provides a tosyl leaving group on a PEG7 spacer, enabling efficient substitution reactions with nucleophiles while enhancing solubility and flexibility for diverse conjugation applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.