Thiol-PEG6-alcohol
This product is a heterobifunctional PEG6 linker featuring a terminal thiol for selective conjugation and a hydroxyl group for derivatization. The PEG6 spacer provides hydrophilicity, flexibility, and medium chain length, making it especially useful for bioconjugation, drug delivery, and surface modification.
Key Features and Benefits:
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Thiol Group: Reacts efficiently with maleimides, haloacetyls, and disulfide exchange.
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Hydroxyl Group: Provides a handle for further activation or functionalization.
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PEG6 Spacer: Balances solubility and steric flexibility for efficient conjugation.
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High Purity: Ensures reproducibility in sensitive workflows.
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Dual Reactivity: Supports stepwise and orthogonal bioconjugation strategies.
Applications:
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Bioconjugation: Thiol-mediated attachment of proteins, peptides, and biomolecules.
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Drug Delivery: PEGylated linker improves solubility, stability, and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
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Synthetic Chemistry: Versatile intermediate for PEGylated scaffold construction.
Storage and Handling:
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Storage: Store at –20 °C, protected from moisture and light.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain thiol and hydroxyl stability.
This product provides dual functionality with a medium-length PEG spacer, making it an especially powerful tool for conjugation, reversible chemistry, and advanced material science.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
