Tetrazine-PEG4-Alkyne is a versatile reagent combining a tetrazine group for rapid, bioorthogonal IEDDA reactions with strained alkenes (e.g., TCO) and an alkyne group for click chemistry applications. The PEG4 spacer enhances solubility, reduces steric hindrance, and ensures compatibility with biological and chemical systems. It is widely used in bioconjugation, imaging, and material science.
Features
- Tetrazine Group: Enables fast and selective IEDDA reactions.
- Alkyne Group: Compatible with azide-based click chemistry for efficient conjugation.
- PEG4 Spacer: Improves solubility and reduces steric interference.
- High Purity: ≥95% for reproducible results.
- Biocompatibility: Suitable for biological and chemical research applications.
Applications
- Bioconjugation: Dual labeling of biomolecules using IEDDA and click chemistry.
- Imaging: Development of fluorescent or radiolabeled probes.
- Diagnostics: Functionalization for biosensors and assays.
- Material Science: Synthesis of functionalized polymers and hydrogels.
- Chemical Biology: Studies in live cells and complex environments.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
