Tetra-PEG4-Methyltetrazine is a multifunctional molecule featuring four PEG4 spacers and four methyltetrazine groups. It enables rapid and selective inverse electron demand Diels-Alder (IEDDA) reactions with strained alkenes like TCO. The PEG4 spacers provide excellent solubility, flexibility, and reduced steric hindrance, making it ideal for advanced bioconjugation, cross-linking, and material synthesis applications.
Features
- Tetrazine Groups: Highly reactive for fast IEDDA conjugations.
- Multivalency: Four reactive sites for efficient cross-linking.
- PEG4 Spacers: Improve solubility and minimize steric hindrance.
- High Purity: ≥95% for reliable performance.
- Biocompatibility: Suitable for biological and material science applications.
Applications
- Bioconjugation: Multivalent linking of proteins, peptides, or biomolecules.
- Material Synthesis: Cross-linking in hydrogels and polymer networks.
- Imaging: Fluorescent probe labeling via TCO-tetrazine reactions.
- Drug Delivery: Functionalization of delivery vehicles.
- Diagnostics: Development of biosensors and imaging agents.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.