TCO-carbonylamino-benzamido-PEG4 acid
This product is a linker with a TCO group, benzamido unit, PEG4 spacer, and carboxyl group. It specifically supports copper-free click chemistry and amide coupling, with PEG4 providing solubility and spacing for bioconjugation and drug delivery.
Key Features and Benefits
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TCO Group: Enables ultrafast copper-free click chemistry with tetrazines.
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Carboxylic Acid Group: Couples efficiently with amines for stable amide linkages.
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PEG4 Spacer: Provides solubility, flexibility, and reduced steric hindrance.
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Benzamido Core: Adds rigidity for controlled conjugation geometry.
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High Purity: Produced to ≥95% purity for reproducible applications.
Applications
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Bioconjugation: Couples TCO-tagged molecules with amines or tetrazine partners.
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Probe Development: Builds compact dual-functional probes for imaging and diagnostics.
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Drug Delivery: Functions as a PEGylated linker for targeted therapeutics.
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Chemical Biology: Supports orthogonal labeling strategies under physiological conditions.
Storage and Handling
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Storage: Store at –20 °C in a sealed, desiccated container away from light.
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Handling: Use freshly prepared solutions; avoid repeated freeze–thaw cycles.
This product combines rapid TCO click reactivity with a carboxyl handle and PEG solubility, specifically offering a versatile scaffold for advanced conjugation and delivery strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
