t-Boc-N-Amido-PEG5-CH2CO2-NHS Ester (CAS: 2743668-40-6) is a highly versatile reagent designed for bioconjugation, drug delivery, and surface modification. It combines a t-Boc-protected amide, a PEG5 spacer, and an NHS ester, ensuring efficient and controlled conjugation. Moreover, its excellent solubility and stability make it a valuable tool for various research and industrial applications.
Key Features:
- t-Boc Protection: Provides stability during synthesis and allows controlled deprotection when needed, ensuring flexibility in chemical modifications.
- PEG5 Spacer: Improves solubility, enhances flexibility, and increases biocompatibility, making it ideal for biological applications.
- NHS Ester Group: Enables rapid and selective amide bond formation with primary amines, ensuring efficient conjugation.
- Excellent Solubility: Dissolves well in both aqueous and organic solvents, allowing for seamless integration into different experimental setups.
- High Purity: Delivers reliable, reproducible results, making it suitable for both research and industrial use.
Applications:
- Bioconjugation: Effectively links biomolecules such as proteins, peptides, and antibodies, supporting therapeutic and diagnostic advancements.
- Drug Delivery: Enhances solubility and stability of active compounds, playing a crucial role in targeted drug delivery systems.
- Surface Modification: Functionalizes nanoparticles, biosensors, and microarrays, expanding possibilities in biomedical and material science applications.
- Polymer Chemistry: Facilitates the synthesis of PEG-based polymer conjugates, contributing to advanced drug formulation and nanotechnology developments.
Conclusion:
In summary, t-Boc-N-Amido-PEG5-CH2CO2-NHS Ester is an essential reagent for modern chemical and biomedical research. With its combination of a t-Boc-protected amide, a flexible PEG5 linker, and a reactive NHS ester, it ensures precise and efficient conjugation. Additionally, its high purity, excellent stability, and broad solubility make it an outstanding choice for bioconjugation, drug delivery, and surface engineering applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
