Propargyl-PEG3-Pyrene
This product is a heterobifunctional fluorescent linker featuring a propargyl (alkyne) group for click chemistry and a pyrene moiety for strong fluorescence labeling. The PEG3 spacer enhances solubility and flexibility, making it especially valuable for probe development, imaging, and multifunctional bioconjugation.
Key Features and Benefits:
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Propargyl Group: Enables CuAAC or SPAAC click chemistry with azides.
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Pyrene Moiety: Provides strong blue fluorescence for detection and imaging.
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PEG3 Spacer: Improves solubility and minimizes steric hindrance.
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Dual Functionality: Combines fluorescence and bioorthogonal reactivity.
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High Purity: Ensures reproducible results in sensitive workflows.
Applications:
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Probe Development: Builds fluorescent probes for diagnostics and imaging.
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Bioconjugation: Couples biomolecules via alkyne handles with integrated fluorescence.
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Drug Delivery: Supports PEGylated scaffolds with built-in optical tracking.
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Synthetic Chemistry: Provides a modular fluorescent building block.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); protect pyrene from prolonged light exposure.
This product integrates click-ready alkyne functionality with pyrene fluorescence in a compact PEG3 scaffold, specifically offering versatility for optical probe design and bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.