Propargyl-PEG3-methyl ester linker contains propargyl group and methyl ester moieties. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The PEG spacer increases the aqueous solubility of the resulting compound. Methyl ester can be hydrolyzed under strong basic condition.
AxisPharm offers 4000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.