Propargyl-PEG24-amine
This product is a heterobifunctional PEG24 linker with a terminal propargyl (alkyne) group for click chemistry and a primary amine for amide coupling. The extended PEG24 spacer specifically provides excellent hydrophilicity, flexibility, and long-range spacing, making it highly useful for bioconjugation, drug delivery, and advanced material engineering.
Key Features and Benefits:
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Propargyl Group: Enables CuAAC and SPAAC click chemistry with azides.
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Amine Group: Couples efficiently with carboxyls, NHS esters, and electrophiles.
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PEG24 Spacer: Provides very long hydrophilic spacing with reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive conjugation workflows.
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Dual Reactivity: Supports orthogonal and multistep bioconjugation strategies.
Applications:
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Click Chemistry: Bioorthogonal azide–alkyne ligation for labeling and probe design.
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Bioconjugation: Dual-functional linker for proteins, peptides, and biomolecules.
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Drug Delivery: PEGylated linker improves solubility, stability, and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve alkyne and amine reactivity.
This product combines click-ready alkyne functionality with an amine handle in a long PEG chain, making it an especially excellent tool for advanced conjugation, drug delivery, and biomaterial design.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
