Poly(DL-lactide) (PDLLA), MW 300-500K

Poly(DL-lactide) (PDLLA), MW 300-500K is a high-molecular-weight biodegradable polyester derived from DL-lactide. Its amorphous polymer structure, mechanical integrity, and hydrolytic degradability make it especially suitable for drug delivery, controlled release, scaffold fabrication, tissue engineering, and biomaterial research.

Key Features and Benefits

• High Molecular Weight: The 300-500K molecular weight range provides substantial chain entanglement, mechanical integrity, and structural stability for polymer fabrication.
• Biodegradable Polyester: PDLLA contains hydrolyzable ester linkages that specifically support gradual polymer degradation under appropriate conditions.
• Amorphous Polymer Structure: The random distribution of D- and L-lactide units limits crystallization, giving PDLLA a predominantly amorphous structure.
• Mechanical Integrity: High-molecular-weight PDLLA provides useful structural properties for biodegradable polymer matrices and fabricated materials.
• Controlled Degradation: The amorphous polyester structure supports hydrolytic degradation specifically for controlled-release and biomaterial applications.
• Versatile Polymer Processing: Supports fabrication into films, fibers, particles, porous scaffolds, coatings, and other polymer structures using appropriate processing methods.
• Biomaterial Platform: Provides a versatile biodegradable polymer matrix for drug delivery, tissue engineering, controlled release, and biomaterial development.

Applications

• Drug Delivery: Supports development of biodegradable particles, matrices, and drug-delivery systems.
• Controlled Release: Provides a biodegradable polymer matrix for sustained and controlled-release formulation research.
• Tissue Engineering: Supports fabrication of biodegradable matrices and scaffolds for tissue engineering research.
• Scaffold Fabrication: Suitable for preparation of porous scaffolds, membranes, films, fibers, and related polymer structures.
• Electrospinning: Supports preparation of PDLLA fibers and fibrous matrices for biomaterial research.
• Polymer Processing: Supports research involving solvent casting, extrusion, molding, and other compatible polymer-processing techniques.
• Biomaterial Research: Supports development of biodegradable polymer systems, composites, coatings, and related biomaterials.

Storage and Handling

• Storage: Store in a tightly sealed container under cool, dry conditions. Protect from moisture and excessive heat during long-term storage.
• Handling: Protect from moisture because hydrolysis can reduce polymer molecular weight. Dry the polymer appropriately before melt processing or other moisture-sensitive applications.

This product provides a high-molecular-weight, amorphous biodegradable polyester with mechanical integrity, processability, and controlled degradation. It specifically supports drug delivery, scaffold fabrication, tissue engineering, controlled release, and biomaterial research.