Poly(ε-Caprolactone)-PEG-Poly(ε-Caprolactone) (PCL-PEG-PCL), MW x 6K, n 4K is an amphiphilic triblock copolymer composed of poly(ε-caprolactone) (PCL) and polyethylene glycol (PEG). It also has hydrophobic PCL blocks positioned on both sides of the hydrophilic PEG segment. This grade combines approximately 6K PCL with 4K PEG, providing a moderately PCL-rich architecture for polymer self-assembly, drug delivery, controlled release, hydrogel development, and biomaterial research.
Key Features and Benefits
- Amphiphilic Triblock Copolymer: Combines hydrophobic PCL end blocks with a hydrophilic PEG central block for polymer assembly, drug delivery, and biomaterial development.
- PCL MW 6K: Provides biodegradable hydrophobic segments specifically for structural support, hydrophobic interactions, and incorporation of hydrophobic compounds.
- PEG MW 4K: Provides a hydrophilic central segment specifically for aqueous compatibility, hydration, and steric stabilization.
- Moderately PCL-Rich Architecture: The 1.5:1 PCL-to-PEG molecular weight ratio provides greater hydrophobic character while retaining a substantial hydrophilic PEG component.
- PCL-PEG-PCL Architecture: The symmetric triblock structure places hydrophobic PCL blocks on both sides of PEG, supporting intermolecular association and formation of organized polymeric structures.
- Biodegradable Polymer Platform: Combines biodegradable PCL with hydrophilic PEG in a versatile polymer platform for drug delivery and biomaterial research.
Applications
- Polymer Self-Assembly: Supports formation of organized amphiphilic structures through association of hydrophobic PCL blocks in aqueous environments.
- Nanoparticle Formulation: Supports preparation of PCL-containing polymeric nanoparticles and other nanoscale delivery systems.
- Drug Delivery: Supports polymeric carriers for hydrophobic compounds and controlled-delivery research.
- Hydrogel Development: Supports development of physically associated and crosslinked polymer networks for hydrogel research.
- Controlled Release: Provides a biodegradable polymer matrix for sustained and controlled-release applications.
- Biomaterial Development: Supports development of biodegradable polymer systems, scaffolds, coatings, and other functional biomaterials.
- Tissue Engineering Research: Supports investigation of PCL-PEG-PCL materials for scaffolds, matrices, and other tissue-engineering applications.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry conditions.
- Handling: Protect from moisture and excessive heat. Allow the material to equilibrate to room temperature before opening to minimize moisture condensation.
This product combines hydrophobic PCL blocks with hydrophilic PEG in a moderately PCL-rich amphiphilic triblock architecture. It specifically supports polymer self-assembly, nanoparticle formulation, drug delivery, controlled release, hydrogel development, tissue engineering, and biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.