PLGA Amine Capped (50:50), MW 40K is a biodegradable PLGA polymer with terminal amine functionality and an approximate molecular weight of 40 kDa. Its 50:50 lactide:glycolide composition specifically supports bioconjugation, drug delivery, nanoparticle formulation, and biomaterial development.
Key Features and Benefits
- Amine Capped: Provides terminal amine functionality for conjugation and further derivatization.
- 50:50 PLGA Ratio: Combines lactide and glycolide in an equal ratio for versatile biodegradable polymer formulations.
- MW 40K: Supports durable polymer matrices, particle formation, and controlled-release applications.
- Versatile Reactivity: The amine group reacts with NHS esters, activated carboxyl groups, and other amine-reactive compounds.
- Biodegradable: PLGA hydrolyzes into lactic acid and glycolic acid under physiological conditions.
Applications
- Bioconjugation: Couples PLGA with peptides, proteins, ligands, dyes, and other functional molecules.
- Drug Delivery: Supports biodegradable controlled and sustained-release formulations.
- Nanoparticles: Enables preparation and functionalization of polymeric nanoparticles and drug carriers.
- Polymer Modification: Provides a reactive amine for attaching linkers, targeting ligands, and other functional groups.
- Biomaterials: Supports biodegradable matrices, coatings, scaffolds, and other material systems.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to limit premature hydrolysis and polymer degradation.
PLGA Amine Capped (50:50), MW 40K combines biodegradable 50:50 PLGA with terminal amine functionality to specifically support bioconjugation, controlled drug delivery, nanoparticle functionalization, polymer modification, and advanced biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.