PEG9-Tos
This product is a monofunctional PEG linker with a tosyl (p-toluenesulfonyl) reactive group and a PEG9 spacer. The tosyl group enables substitution with nucleophiles, making it an especially versatile intermediate for custom linker synthesis and functionalization.
Key Features and Benefits
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Tosyl Group: Excellent leaving group for substitution with thiols, amines, or alkoxides.
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PEG9 Spacer: Provides solubility and flexibility while reducing steric hindrance.
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Reactive Intermediate: Serves as a precursor for diverse PEG-based derivatives.
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High Versatility: Supports small-molecule conjugation and polymer modification.
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High Purity: Ensures reproducibility in advanced synthesis workflows.
Applications
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Organic Synthesis: Prepares functional PEG derivatives via nucleophilic substitution.
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Bioconjugation: Builds custom PEGylated linkers for proteins, peptides, or probes.
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Material Science: Introduces PEG functionality into polymers or nanostructures.
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Drug Delivery: Constructs PEG scaffolds for improved solubility and stability.
Storage and Handling
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Storage: Keep at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product combines a tosyl leaving group with a PEG9 spacer, specifically providing a reactive and soluble intermediate for linker synthesis and bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
