PEG3-tetrazine is a unique bifunctional linker, featuring a triethylene glycol (PEG3) spacer connected to a highly reactive tetrazine moiety. The PEG3 component offers enhanced solubility and reduced immunogenicity, while the tetrazine group facilitates rapid bioorthogonal click reactions. This combination ensures efficient and selective conjugation, making PEG3-tetrazine an indispensable tool in modern chemical biology.
In pharmaceutical research and development, PEG3-tetrazine plays a pivotal role in the construction of bioconjugates for targeted drug delivery and imaging applications. The linker’s superior reactivity and biocompatibility allow for the synthesis of complex, multifunctional molecules, such as antibody-drug conjugates and nanoparticles. As a result, PEG3-tetrazine accelerates drug discovery processes, expedites the development of precision therapeutics, and enhances the understanding of biological mechanisms.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.