PC Biotin-PEG3-Alkyne (CAS: 1869922-24-6) is a photocleavable biotinylation reagent designed for bioconjugation and controlled biomolecule release. It features a biotin group linked to an alkyne through a triethylene glycol (PEG3) spacer and a photocleavable linker. The alkyne group supports copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the photocleavable linker enables biomolecule release under near-UV light (around 365 nm).
Key Features:
- Functional Groups: Biotin for affinity capture, alkyne for CuAAC, and a photocleavable linker for light-induced release.
- Molecular Formula: C₃₅H₅₂N₆O₁₂S
- Molecular Weight: 780.89 g/mol
- Purity: Typically ≥95%
Applications:
- Bioconjugation: Enables biotin labeling of azide-functionalized molecules for purification or detection.
- Photorelease Studies: Allows precise light-triggered biomolecule release, ideal for studying dynamic protein interactions.
- Proteomics and Genomics: Supports the isolation and analysis of proteins and nucleic acids through biotin-streptavidin binding.
- Drug Delivery Research: Useful in light-responsive drug delivery systems for controlled therapeutic release.
This versatile reagent ensures efficient bioconjugation, controlled release, and high compatibility with biological research and diagnostic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
