N,N-Bis(PEG2-propargyl)-N-amido-PEG2-thiol
CAS: 2752068-02-1
Description:
N,N-Bis(PEG2-propargyl)-N-amido-PEG2-SH is a multifunctional crosslinker featuring two alkyne groups and a -SH group, all connected by PEG2 (polyethylene glycol) spacers. This design allows for copper-catalyzed click chemistry with azides via the alkyne groups and thiol-based conjugation with thiol-reactive molecules, making it highly versatile for bioconjugation applications.
Key Features:
- Dual Propargyl Groups: Enables copper-catalyzed click chemistry with azide-functionalized biomolecules.
- Thiol Group: Allows for conjugation with thiol-reactive entities, such as maleimide groups.
- PEG2 Linkers: Improves solubility and flexibility, enhancing compatibility with biological environments.
Applications:
- Bioconjugation: Suitable for creating multifunctional biomolecule conjugates through both click chemistry and thiol-based reactions.
- Drug Delivery: Useful in developing complex drug delivery systems with controlled release properties.
- Molecular Assembly: Ideal for constructing advanced molecular structures in biomedical research.
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