N,N-Bis(PEG1-azide)
N,N-Bis(PEG1-azide) is a high-purity bifunctional PEG linker specifically with two terminal azide groups for copper-catalyzed (CuAAC) or strain-promoted (SPAAC) click chemistry. The short PEG1 spacers specifically improve solubility, flexibility, and reduce steric hindrance, enabling efficient multi-site conjugation in both aqueous and organic systems. This reagent is especially ideal for crosslinking, multi-valent bioconjugation, and the synthesis of multifunctional biomolecules and materials.
Key Features and Benefits
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Dual Azide Groups: Support multi-site click conjugation with alkynes.
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PEG1 Spacers: Enhance solubility and molecular flexibility.
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Bifunctional Design: Enables crosslinking and multi-valent functionalization.
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High Purity: Supplied at >95% purity for reproducibility.
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Versatile Utility: Compatible with CuAAC and SPAAC click chemistry.
Applications
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Crosslinking of alkyne-functionalized biomolecules.
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Multi-valent conjugation for nanoparticle and polymer modification.
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Synthesis of multifunctional probes and materials.
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Scaffold design for drug delivery or diagnostics.
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Hydrogel and biomaterial network formation.
Storage and Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Handling: Use anhydrous solvents; avoid prolonged exposure to moisture.
This product offers two azide groups connected by PEG1 spacers for especially efficient, flexible, and high-yield click chemistry in multi-site conjugation and crosslinking applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
