N,N-Bis(PEG1-amine)-N-Boc
This product is a multifunctional PEG-based reagent featuring two terminal amines and one Boc-protected amine. The PEG1 arms provide solubility and flexibility, while the Boc group allows orthogonal protection, making it useful for controlled synthesis and bioconjugation strategies.
Key Features and Benefits:
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Dual Primary Amines: React with carboxyls, NHS esters, or other electrophiles.
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Boc-Protected Amine: Provides acid-labile orthogonal protection for stepwise synthesis.
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PEG1 Units: Improve hydrophilicity and reduce steric hindrance.
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Multifunctional Design: Supports branched and controlled conjugation.
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High Purity: Ensures reproducibility in complex workflows.
Applications:
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Bioconjugation: Couples biomolecules with dual amines and orthogonal protection.
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Drug Delivery: PEGylated design enhances solubility and flexibility.
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Synthetic Chemistry: Intermediate for multifunctional scaffolds and branched PEG systems.
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Material Science: Supports surface modification and polymer engineering.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMSO, DMF); avoid premature deprotection.
This product provides dual reactivity with orthogonal protection in a compact PEG scaffold, making it an especially versatile building block for synthesis, drug delivery, and conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
