NH-bis(PEG3-t-butyl ester)
This product is a multifunctional PEG reagent featuring a central amine connected to two PEG3 arms terminating in acid-labile t-butyl esters. This design provides excellent solubility, orthogonal reactivity, and controlled deprotection, making it especially useful for bioconjugation, drug delivery, and multifunctional synthesis.
Key Features and Benefits:
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Dual t-Butyl Esters: Provide acid-labile protection for controlled release.
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Central Amine Core: Serves as a branching scaffold for conjugation.
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PEG3 Arms: Enhance solubility, flexibility, and steric accessibility.
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Orthogonal Reactivity: Supports stepwise and multifunctional synthetic strategies.
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High Purity: Ensures reproducibility in advanced workflows.
Applications:
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Bioconjugation: Couples biomolecules with controlled ester deprotection.
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Drug Delivery: Provides PEGylated scaffolds with cleavable ester handles.
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Probe Development: Builds multifunctional linkers for diagnostics.
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Synthetic Chemistry: Enables modular, orthogonal linker synthesis.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); deprotect esters under acidic conditions.
This product combines dual ester-protected PEG arms with an amine core, specifically offering solubility and orthogonal reactivity for advanced conjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
