N6-Methyl-dA phosphoramidite

N6-Methyl-dA Phosphoramidite, 5′-O-DMTr-N6-methyl-2′-deoxyadenosine (CAS: 105931-58-6) is a modified adenosine used in DNA synthesis. It features a N6-methylated deoxyadenosine with a 5′-O-DMTr protecting group. This allows for easy incorporation of methylated adenosine into synthetic DNA. The modification is important for studying epigenetics and gene regulation.

Applications:

• Oligonucleotide Synthesis: Adds N6-methyladenosine to DNA strands.
• Epigenetics Research: Explores the role of m6A in gene expression.
• Methylation Studies: Investigates how DNA methylation affects biological functions.