Azido-PEG3-acid
This product is a heterobifunctional PEG linker containing a terminal azide group, a PEG3 spacer, and a carboxylic acid. It specifically enables click chemistry with alkynes and amide coupling, offering solubility, compact length, and dual reactivity.
Key Features and Benefits
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Azide Group: Reacts with alkynes via CuAAC or SPAAC click chemistry.
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Carboxylic Acid: Couples efficiently with primary amines to form amide bonds.
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PEG3 Spacer: Provides solubility while maintaining compact flexibility.
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Dual Reactivity: Combines click chemistry with amide coupling.
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High Purity: Ensures reproducibility in sensitive bioconjugation workflows.
Applications
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Bioconjugation: Links azide-modified biomolecules with amine partners.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Provides PEG scaffolds with click and amide reactivity.
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Material Science: Functionalizes nanoparticles, polymers, and surfaces with dual handles.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates azide click chemistry with carboxyl functionality in a PEG3 scaffold, specifically offering solubility and dual conjugation capability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
