N-Hydroxysuccinimidyl-4-azidobenzoate, 4-Azidobenzoic acid NHS ester (CAS: 53053-08-0) is a heterobifunctional crosslinker commonly used in bioconjugation and molecular labeling. It has two reactive groups: an NHS ester that forms stable amide bonds with primary amines, and an aryl azide that generates a reactive nitrene upon UV irradiation, enabling covalent attachment to various functional groups.
Key Features:
- NHS Ester: Reacts with primary amines, forming stable amide bonds.
- Aryl Azide Group: Creates a reactive nitrene upon UV light exposure, allowing covalent bonding with multiple biomolecules.
Applications:
- Bioconjugation: Links proteins, peptides, and other biomolecules for research and diagnostics.
- Crosslinking Reagent: Studies protein-protein interactions and creates multifunctional molecular structures.
Handling Tip: Store at -20°C and avoid light exposure to maintain stability. This versatile linker is ideal for chemical biology, protein interaction studies, and advanced molecular assembly.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
