Azide-PEG4-Ms
Azide-PEG4-Ms is a high-purity heterobifunctional PEG linker containing an azide group for copper-catalyzed or strain-promoted click chemistry, and a mesylate (methanesulfonate) group for nucleophilic substitution with various functional groups such as amines, thiols, or alcohols. The PEG4 spacer specifically improves water solubility and reduces steric hindrance, enabling efficient and selective bioconjugation in both aqueous and organic media.
Key Features
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Azide group for bioorthogonal click chemistry (CuAAC or SPAAC)
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Mesylate group for versatile nucleophilic substitution reactions
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PEG4 spacer for solubility and reduced steric hindrance
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Suitable for both aqueous and organic synthesis environments
Applications
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Synthesis of multifunctional bioconjugates
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Click chemistry-based labeling and modification
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Preparation of PEGylated biomolecules or nanoparticles
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Custom linker design for targeted drug delivery
Storage and Handling
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Store at –20 °C, protected from light and moisture
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Allow to warm to room temperature before opening
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Avoid repeated freeze-thaw cycles
This product offers dual reactivity through its azide and mesylate groups, enabling efficient conjugation strategies specifically for complex molecule assembly, bioorthogonal labeling, and advanced material synthesis.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
