m-PEG4-Hydrazide
m-PEG4-Hydrazide is a high-purity PEG derivative with a terminal hydrazide group on a PEG4 spacer, enabling conjugation with aldehydes and ketones while improving solubility and flexibility.
Key Features and Benefits
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Hydrazide Group – Selectively reacts with aldehydes and ketones to form stable hydrazone linkages.
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PEG4 Spacer – Provides solubility, flexibility, and reduced steric hindrance in conjugates.
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Monofunctional PEG – Ensures controlled labeling and predictable conjugation outcomes.
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High Purity – Suitable for bioconjugation, biomolecule modification, and probe development.
Applications
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Conjugation with aldehyde- or ketone-containing biomolecules
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Preparation of hydrazone-linked bioconjugates
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Antibody, peptide, and protein modification
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Use in drug delivery systems and diagnostics
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents (e.g., DMF, DMSO). Avoid repeated freeze–thaw cycles.
m-PEG4-Hydrazide provides a terminal hydrazide group on a PEG4 spacer, enabling efficient conjugation with aldehydes and ketones. Its PEG backbone specifically enhances solubility and flexibility, making it ideal for bioconjugation and drug delivery applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
