m-PEG3-Hydrazide
This product is a high-purity PEG derivative featuring a hydrazide functional group for selective conjugation with aldehydes and ketones. The short PEG3 spacer specifically provides solubility and flexibility, while minimizing steric hindrance.
Key Features and Benefits
-
Hydrazide Group – Reacts with aldehydes and ketones to form stable hydrazone bonds.
-
PEG3 Spacer – Enhances aqueous solubility and reduces aggregation.
-
Monofunctional PEG – Provides a single reactive hydrazide group for controlled conjugation.
-
High Purity – Suitable for bioconjugation, probe development, and drug delivery applications.
Applications
-
Conjugation to oxidized glycans, glycoproteins, and polysaccharides
-
Labeling of aldehyde- or ketone-containing biomolecules
-
Preparation of PEGylated bioconjugates and biomaterials
-
Development of diagnostic probes and delivery systems
Storage & Handling
-
Storage: Store at –20 °C, dry, and protected from light.
-
Use: Dissolve in anhydrous solvents (e.g., DMF, DMSO) or aqueous buffer as required. Avoid repeated freeze–thaw cycles.
m-PEG3-Hydrazide enables efficient conjugation of aldehyde- and ketone-containing biomolecules through hydrazone bond formation. The PEG3 spacer enhances solubility and provides flexibility, making it an especially reliable tool for bioconjugation, labeling, and drug delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
