m-PEG3-CH2COOH (CAS: 16024-60-5) is a polyethylene glycol (PEG) derivative with a carboxylic acid group at one end. Its PEG3 spacer improves water solubility, reduces immunogenicity, and enhances biocompatibility, making it ideal for drug delivery and bioconjugation applications.
Key Features:
- Carboxylic Acid Group: Allows easy attachment to amine-containing molecules through amide bond formation.
- PEG3 Spacer: Increases solubility, stability, and biocompatibility while reducing immune responses.
Applications:
- Drug Delivery: Used in creating prodrugs and antibody-drug conjugates (ADCs) for better drug stability and delivery.
- Bioconjugation: Links biomolecules like proteins, peptides, and imaging probes for diagnostics and therapeutics.
How to Use:
- Storage: Keep in a sealed container at room temperature, away from moisture and light.
- Solubility: Easily dissolves in organic solvents like DMSO and methanol for use in various reactions.
m-PEG3-CH2COOH is a versatile tool in pharmaceutical research, offering improved solubility, stability, and compatibility for advanced therapeutic and diagnostic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.