m-PEG3-CH2-acid chloride
This product is a monofunctional PEG linker containing a methoxy end group, a PEG3 spacer, and a reactive acid chloride. It specifically enables acylation, esterification, and amide bond formation, offering solubility, compact flexibility, and strong reactivity.
Key Features and Benefits
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Acid Chloride Group: Reacts efficiently with alcohols and amines for ester and amide formation.
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Methoxy End Group: Provides stability and hydrophilic character.
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PEG3 Spacer: Enhances solubility while maintaining compact length.
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High Reactivity: Suitable for rapid acylation and derivatization.
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High Purity: Ensures reproducibility in synthesis and conjugation workflows.
Applications
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Bioconjugation: Couples PEG scaffolds to biomolecules via ester or amide chemistry.
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Organic Synthesis: Serves as an intermediate for PEG-based linker development.
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Probe Development: Builds functional probes with PEGylated scaffolds.
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Drug Delivery: Provides reactive PEG intermediates for conjugation.
Storage and Handling
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Storage: Store at –20 °C in a sealed, moisture-protected container.
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Handling: Use under anhydrous conditions; handle quickly to avoid hydrolysis.
This product integrates acid chloride reactivity with a PEG3 scaffold, specifically offering solubility, compact length, and versatile acylation capability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
