Methyltetrazine-PEG9-acid is a building block used to derivatize of amine containing biomolecules. The resulting tetrazine containing biomolecule can readily react with TCO bearing biomolecules. Tetrazine demonstrates exceptionally fast cycloaddition kinetics (up to 30 000 M-1 s-1) with trans-cyclooctene (TCO) as the dienophile. It is the fastest kinetics ever reported for any bioorthogonal reactions.
AxisPharm offers 4000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.