Methylcyclopropene-PEG1-NHS carbonate CAS:1454558-59-8 is a chemical compound that contains several functional groups, including a cyclopropene group, a PEG (polyethylene glycol) chain, and an NHS carbonate ester group. This compound is often used in the field of bioconjugation, which involves the covalent attachment of two or more molecules to form a complex that retains the properties of each individual component.
In bioconjugation, Methylcyclopropene-PEG1-NHS carbonate can be used as a linker that can react with primary amines in proteins or other biomolecules to form stable amide bonds. The NHS carbonate ester group in the linker enables the formation of a highly reactive intermediate that can selectively react with primary amines under mild conditions. The PEG chain improves the solubility and biocompatibility of the linker, while the cyclopropene group can be used for further functionalization or modification of the bioconjugate.
Methylcyclopropene-PEG1-NHS carbonate is a valuable tool for bioconjugation and drug delivery applications, as it can improve the pharmacokinetics and efficacy of drugs, as well as reduce their toxicity and immunogenicity. Its unique combination of functional groups makes it an essential component of modern pharmaceutical research and a promising candidate for the development of targeted therapeutics in various diseases.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.