Mal-PEG2-Azide
CAS: 2253965-07-8
Description:
Mal-PEG2-Azide is a versatile linker molecule featuring a maleimide group and an azide group connected by a PEG2 (polyethylene glycol) spacer. The maleimide reacts specifically with thiol groups, while the azide enables copper-free click chemistry with alkynes, making it ideal for bioconjugation and drug delivery applications.
Key Features:
- Maleimide Group: Binds specifically to thiol-containing molecules, such as cysteine residues in proteins.
- Azide Group: Allows for copper-free click chemistry with alkyne-functionalized molecules, enabling efficient and bioorthogonal conjugation.
- PEG2 Spacer: Enhances solubility and flexibility, reducing steric hindrance for effective conjugation.
Applications:
- Bioconjugation: Links thiol- and alkyne-containing biomolecules for targeted labeling and modifications.
- Drug Delivery: Useful in constructing stable drug delivery systems with precise targeting capabilities.
- Protein and Antibody Labeling: Facilitates the creation of multifunctional conjugates in biochemical research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
