Mal-PEG16-NHS

Mal-PEG16-NHS is a bi-functional PEG linker with a maleimide group and an NHS ester.

Key Features

1. Dual Functional Groups:
   • Maleimide: Reacts with thiol groups (-SH) to form stable thioether bonds.
   • NHS Ester: Conjugates with primary amines to create stable amide bonds.
2. PEG Linker:
   • Enhances solubility and biocompatibility.
   • Flexible 16-unit PEG chain (~900 Da) minimizes steric hindrance in conjugation reactions.
3. Versatile:
   • Suitable for applications requiring dual functionalization in aqueous or organic environments.

Applications

1. Bioconjugation:
   • Links biomolecules, such as peptides, proteins, or antibodies, via thiol and amine groups.
   • Ideal for creating complex biomolecular systems.
2. Drug Delivery:
   • Acts as a linker in drug conjugates to improve pharmacokinetics and targeting.
3. Surface Modification:
   • Functionalizes surfaces of nanoparticles, biosensors, or implants for biomedical use.
4. Nanotechnology:
   • Enables dual labeling or functionalization in advanced nanoscale systems.

Storage and Handling

• Storage: Store at -20°C in a dry, tightly sealed container, away from light and moisture.
• Handling: Use gloves and handle in a dry environment to preserve reactivity.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.