m-PEG8-thiol
This product is a high-purity methoxy-PEG derivative with a terminal thiol group connected by a PEG8 spacer, specifically designed for selective conjugation with maleimides, gold surfaces, or other thiol-reactive groups.
Key Features and Benefits
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Methoxy End Group – Provides stability and minimizes non-specific interactions.
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Thiol Group – Enables site-specific conjugation to maleimides, disulfides, or metal surfaces.
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PEG8 Spacer – Enhances solubility, flexibility, and reduces steric hindrance in conjugates.
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High Purity – Suitable for bioconjugation, surface functionalization, and nanotechnology.
Applications
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Conjugation of proteins, peptides, or antibodies to maleimide-functionalized molecules
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Immobilization on gold nanoparticles or thiol-reactive surfaces
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Development of drug delivery systems and biomaterials
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Surface modification in biosensor and diagnostic platforms
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Handling: Dissolve in anhydrous solvents (e.g., DMF, DMSO). Avoid oxidation of thiol groups by working under inert atmosphere when possible.
This product provides a stable methoxy end group and a reactive thiol moiety on a PEG8 spacer, specifically enabling efficient bioconjugation, surface immobilization, and nanotechnology applications with improved solubility and reduced steric hindrance.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.