m-PEG6-Ms
This product is a monofunctional PEG linker featuring a mesyl (methanesulfonyl) reactive group and a PEG6 spacer. The mesyl group acts as an excellent leaving group, specifically enabling nucleophilic substitution for custom PEG derivatives in synthesis and bioconjugation.
Key Features and Benefits
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Mesyl Group: Highly reactive leaving group for substitution with thiols, amines, or alkoxides.
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PEG6 Spacer: Provides solubility and flexibility while minimizing steric hindrance.
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Reactive Intermediate: Serves as a precursor for functional PEG-based linkers.
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Compact Design: Balances solubility with manageable molecular size.
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High Purity: Ensures reproducible performance in sensitive applications.
Applications
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Organic Synthesis: Prepares diverse PEG derivatives via mesyl substitution.
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Bioconjugation: Builds PEGylated linkers for proteins, peptides, or probes.
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Material Science: Incorporates PEG functionality into polymers and nanostructures.
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Drug Delivery: Constructs PEG scaffolds for enhanced solubility and stability.
Storage and Handling
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Storage: Keep at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO to maintain reactivity.
This product combines a mesyl leaving group with a PEG6 spacer, providing a reactive and soluble intermediate specifically for linker synthesis, bioconjugation, and advanced material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
