IR 750 Acid is a near-infrared (NIR) fluorescent dye containing a carboxylic acid functional group. It specifically supports NIR fluorescence labeling, bioconjugation, imaging research, probe development, and functional material design.
Key Features and Benefits
- Near-Infrared Fluorophore: Provides fluorescence in the NIR spectral region for fluorescence-based detection and imaging research.
- Carboxylic Acid Functionality: The –COOH group provides a reactive site specifically for conjugation with compatible amine-containing molecules after activation.
- Amine-Reactive Conjugation: Carboxyl activation methods such as EDC/NHS chemistry support formation of stable amide linkages.
- NIR Detection: Near-infrared fluorescence can specifically reduce interference from many shorter-wavelength fluorescent signals.
- Fluorescent Labeling: Supports incorporation of an NIR fluorescent signal into compatible molecules, polymers, particles, and surfaces.
- Versatile Conjugation Platform: The carboxyl group specifically enables modification with suitable amine-containing ligands, biomolecules, and polymers.
- Probe Development: Supports preparation of fluorescent probes and conjugates for analytical and imaging research.
Applications
- NIR Fluorescence Imaging: Supports near-infrared fluorescence detection and imaging studies.
- Bioconjugation: Enables attachment to compatible amine-containing peptides, proteins, polymers, and other molecules.
- EDC/NHS Coupling: Supports carboxyl activation followed by reaction with primary amines.
- Fluorescent Labeling: Enables NIR labeling of compatible biomolecules, polymers, nanoparticles, and surfaces.
- Nanoparticle Functionalization: Supports incorporation of NIR fluorescence into compatible nanoparticle systems.
- Probe Development: Enables preparation of NIR fluorescent probes for analytical and imaging research.
- Polymer Functionalization: Supports conjugation with compatible amine-functionalized polymers and polymeric materials.
- Biomaterial Research: Supports development of fluorescent materials, conjugates, particles, and related research systems.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry conditions and protected from light.
- Handling: Minimize light exposure to reduce photobleaching. Protect from moisture and excessive heat. Allow the material to reach room temperature before opening.
IR 750 Acid combines near-infrared fluorescence with carboxylic acid functionality for versatile conjugation and specifically supports NIR labeling, bioconjugation, probe development, nanoparticle functionalization, and fluorescence imaging research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
