HO-PEG9-t-butyl ester
This product is a heterobifunctional linker featuring a terminal hydroxyl group and an acid-labile t-butyl ester. The PEG9 spacer enhances solubility, flexibility, and spacing, making this reagent especially valuable for orthogonal conjugation, drug delivery, and multifunctional probe development.
Key Features and Benefits:
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Terminal Hydroxyl Group: Provides a functional handle for further modification.
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t-Butyl Ester: Acid-labile protecting group enables controlled deprotection.
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PEG9 Spacer: Enhances solubility, hydrophilicity, and steric accessibility.
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Orthogonal Reactivity: Supports multi-step synthesis strategies.
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High Purity: Ensures reproducibility in sensitive applications.
Applications:
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Bioconjugation: Enables orthogonal linker design for biomolecules.
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Drug Delivery: Supports PEGylated scaffolds with controlled release functionality.
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Probe Development: Builds advanced probes with flexible PEG spacing.
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Material Science: Functionalizes polymers and nanomaterials with precision.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid premature deprotection.
This product integrates a reactive hydroxyl group with an acid-labile ester in a PEG9 scaffold, offering especially versatile functionality for advanced synthesis and bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
