HO-PEG2-t-butyl ester
This product is a high-purity PEG derivative featuring a terminal hydroxyl group and a tert-butyl ester, specifically connected by a PEG2 spacer for solubility and flexibility.
Key Features and Benefits
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Hydroxyl Group – Provides a versatile handle for further functionalization via esterification, etherification, or coupling chemistry.
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tert-Butyl Ester – Can be selectively cleaved under mild acidic conditions to yield the corresponding carboxylic acid.
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PEG2 Spacer – Enhances solubility and flexibility while maintaining a compact structure.
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High Purity – Suitable for bioconjugation, surface modification, and polymer–drug conjugates.
Applications
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Building block for PEGylated intermediates and derivatives
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Synthesis of ester- or acid-functionalized conjugates
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Surface and material modification
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Use in drug delivery, biomaterials, and diagnostics
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents (e.g., dichloromethane, DMF, DMSO). Avoid repeated freeze–thaw cycles.
This product provides a hydroxyl group and a tert-butyl ester on a PEG2 spacer, enabling versatile conjugation, acid generation, and improved solubility specifically for chemical and bioconjugation applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
