Maleimide PEG Hydroxyl (Mal-PEG-OH, HO-PEG-Mal), MW 20K is a heterobifunctional maleimide PEG hydroxyl product commonly used as a crosslinker between two different chemical entities or spacer. Maleimide reacts with thiol, SH, sulfhydryl or sulfhydryl, and hydroxyl can react with carboxylic acid. The PEG moiety in the heterofunctional PEG derivatives provides water solubility, biocompatibility and flexibility. Applications are particularly suitable for the development of antibody drug conjugates (ADCs).
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.