Folate-PEG7-Azide

Folate-PEG7-Azide (Folic Acid-PEG7-Azide)

Folate-PEG7-Azide is a versatile compound designed for advanced drug delivery and bioconjugation applications. It combines folic acid, a polyethylene glycol (PEG8) spacer, and an azide functional group, providing improved solubility, stability, and specificity for targeted drug delivery and diagnostic systems.

Key Features:

• PEG Spacer:
  • Enhances solubility and stability in biological environments.
  • Reduces steric hindrance for efficient bioconjugation.
• Azide Functional Group:
  • Enables bioorthogonal reactions via click chemistry.
  • Facilitates efficient and selective bioconjugation with other molecules.
• Folic Acid Moiety:
  • Targets folate receptors overexpressed in cancer cells.
  • Provides selective delivery for therapeutic or imaging agents.

Applications:

1. Targeted Drug Delivery:
   • Delivers cytotoxic drugs or imaging agents specifically to cancer cells via folate receptor targeting.
   • Reduces off-target effects and improves treatment efficacy.
2. Bioconjugation:
   • Enables attachment of biomolecules such as peptides, proteins, or therapeutic agents through the azide group.
3. Cancer Diagnostics and Therapy:
   • Develops targeted therapies and imaging tools for cancers with overexpressed folate receptors.
4. Research and Development:
   • Facilitates the creation of innovative drug delivery systems and diagnostic tools in biomedical research.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.