Folate-PEG10-NHS ester
This product is a bifunctional linker containing a folate ligand, a PEG10 spacer, and an N-hydroxysuccinimide (NHS) ester. It specifically enables targeted delivery through folate receptor binding and efficient amine conjugation via NHS ester chemistry.
Key Features and Benefits
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Folate Moiety: Provides high-affinity targeting of folate receptors on cancer cells.
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PEG10 Spacer: Enhances solubility, biocompatibility, and molecular flexibility.
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NHS Ester: Couples efficiently with primary amines to form stable amide bonds.
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Targeted Conjugation: Combines receptor-mediated uptake with versatile amine reactivity.
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High Purity: Ensures reproducibility in drug delivery and bioconjugation workflows.
Applications
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Targeted Drug Delivery: Directs therapeutic agents to folate receptor–positive cells.
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Bioconjugation: Couples folate–PEG linkers to proteins, peptides, or nanoparticles.
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Probe Development: Builds folate-functionalized probes for imaging and diagnostics.
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Material Science: Functionalizes polymers and nanostructures with folate and amine chemistry.
Storage and Handling
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Storage: Keep at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates folate receptor targeting with amine-reactive NHS chemistry in a PEG10 scaffold, specifically providing a versatile linker for targeted drug delivery and probe design.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
